Image Analyst MKII provides complex image processing tasks in a biologist-friendly manner.

Fluorescence microscopy image analysis
automation - time series - physiology

Mitochondria:cell volume fraction measurement in INS-1E 
				insulinoma cells

Mitochondria:cell volume fraction measurement in INS-1E insulinoma cells. Red, mitochondria (MitoTracker Red); Green, cells (calcein-AM). From: (17).

Mitochondria:cell volume fraction measurement in INS-1E 
				insulinoma cells

Mitochondria:cell volume fraction measurement in INS-1E insulinoma cells. Binarized image. Yellow, mitochondria (MitoTracker Red); Green, cells (calcein-AM). From: (17).

Mitochondria:cell volume fraction measurement in INS-1E 
				insulinoma cells

Mitochondria:cell volume fraction measurement in INS-1E insulinoma cells. Motage of Raw fluorecence (top left), Binarized calcein fluorescence (top right), highpass filtered MitoTracker Red (bottom left) and Calcein fluorescence (gray) overlaid by mitochondrial segments (bottom right). From: (17).

Mitochondria:cell volume fraction measurement in rat cortical neurons

Mitochondria:cell volume fraction measurement in rat cortical neurons. Highpass filtered MitoTracker Red (left) and Calcein fluorescence (gray) overlaid by mitochondrial segments (right). From: (17).

Human dopaminergic neurons differentiated from induced pluripotent stem cells

Mitochondrial volume fractionator in human dopaminergic neurons differentiated from induced pluripotent stem cells. Different phases of image processing for measurement of mitochondria:cell volume fraction.
From: (24).

Human dopaminergic neurons differentiated from induced pluripotent stem cells

Mitochondrial volume fractionator in human dopaminergic neurons differentiated from induced pluripotent stem cells. Different phases of image processing for measurement of mitochondria:cell volume fraction.
From: (24).

Human pancreatic β-cells. Overlay of the mitochondrial volume fractionator assay and insulin immunostaining

Montage of confocal micrographs of human dispersed islet cells represented as a composite of artificially colored fluorescence channels and processed images used to calculate mitochondria:cell volume fractions in live β-cells. Three imaging modalities of the same individual cells are overlaid by image registration; 1) live imaging: red, mitochondria (MitoTracker Red); blue, cells (calcein-AM); 2) immunostained, fixed-specimen imaging: green: insulin immunofluorescence; white, nuclei (Hoechst 33342); 3) image processing: various colored shapes indicate mitochondrial profiles. One tile of the montage is 22.5 µm wide. From: (26).

Human pancreatic β-cell. Overlay of the mitochondrial volume fractionator assay and insulin immunostaining

Confocal micrograph of human dispersed islet cells represented as a composite of artificially colored fluorescence channels and processed images used to calculate mitochondria:cell volume fractions in live β-cells. Three imaging modalities of the same individual cells are overlaid by image registration; 1) live imaging: red, mitochondria (MitoTracker Red); blue, cells (calcein-AM); 2) immunostained, fixed-specimen imaging: green: insulin immunofluorescence; white, nuclei (Hoechst 33342); 3) image processing: various colored shapes indicate mitochondrial profiles. The image 22.5 µm wide. From: (26).

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